Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475206 | 0.74 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL18173851 | 0.74 | MAPT (0.45) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL6496085 | 0.71 | KDM4E (0.63) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL1249460 | 0.71 | IKBKB (0.51) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL5192550 | 0.71 | KDM4E (0.55) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL18173829 | 0.71 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL14064272 | 0.68 | RAB9A (0.48) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL6503373 | 0.68 | L3MBTL1 (0.57) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL12475734 | 0.68 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL29462096 | 0.68 | KDM4E (0.57) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |