Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171975 | 0.87 | RAB9A (0.68) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL12475206 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL12475734 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL21376152 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL15049359 | 0.72 | RAB9A (0.69) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL10288143 | 0.72 | MAPT (0.45) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL2069278 | 0.71 | RAB9A (1.00) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL1574466 | 0.71 | RAB9A (1.00) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL18179925 | 0.71 | RAB9A (0.48) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL2169817 | 0.71 | RAB9A (0.62) | SMN1; SMN2KDM4ERAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107912-B1 | DERIVATIVES OF 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2024-07-10 | — | — | EP | disclosed |
| EP-3864015-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES | BAYER AG (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-20230087882-A1 | 2-(Het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-03-23 | — | — | US | disclosed |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| US-11274097-B2 | 2-(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-03-15 | — | — | US | disclosed |
| US-20220009930-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-13 | — | — | US | disclosed |
| EP-3257853-B1 | CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | NISSAN CHEMICAL CORP (JP) | 2021-11-10 | — | — | EP | disclosed |
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-11058115-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-07-13 | — | — | US | disclosed |
| US-20210017194-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2021-01-21 | — | — | US | disclosed |
| US-10087192-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-02 | — | — | US | disclosed |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| EP-3286187-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | Syngenta Participations AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| US-20180022760-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20180016273-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20180002345-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-04 | — | — | US | disclosed |
| EP-3257853-A1 | CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274097-B2 | 2-(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents | CYP8B1, CYP4B1, CYP1B1 | SMN1; SMN2 2799/4885KDM4E 2181/4885RAB9A 643/4885 |
| US-20180022760-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | HDAC3, CHRM3, NR1D2 | SMN1; SMN2 4336/4885KDM4E 3586/4885RAB9A 1132/4885 |
| US-20180016273-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP4B1, CYP1B1, CYP8B1 | SMN1; SMN2 3314/4885KDM4E 2049/4885RAB9A 751/4885 |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | DDT, NIT2, SQOR | SMN1; SMN2 996/4885KDM4E 2923/4885RAB9A 1236/4885 |
| US-11058115-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | SMN1; SMN2 2101/4885KDM4E 2375/4885RAB9A 1092/4885 |
| US-20180002345-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP1B1, CYP4B1, CYP8B1 | SMN1; SMN2 3001/4885KDM4E 2544/4885RAB9A 862/4885 |
| US-11083199-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | SMN1; SMN2 2358/4885KDM4E 2112/4885RAB9A 892/4885 |
| US-20230087882-A1 | 2-(Het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | CYP1B1, CYP4B1, CYP8B1 | SMN1; SMN2 3017/4885KDM4E 2694/4885RAB9A 800/4885 |
| US-10087192-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | CYP1B1, CYP4B1, CYP8B1 | SMN1; SMN2 3001/4885KDM4E 2544/4885RAB9A 862/4885 |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CYCS | SMN1; SMN2 3343/4885KDM4E 1838/4885RAB9A 374/4885 |
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP1B1, CYP4B1, CYP8B1 | SMN1; SMN2 3065/4885KDM4E 2639/4885RAB9A 700/4885 |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | EPHX2, CYP8B1, CYP1B1 | SMN1; SMN2 2890/4885KDM4E 2446/4885RAB9A 467/4885 |
| US-20210017194-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | HDAC3, CHRM3, NR1D2 | SMN1; SMN2 4336/4885KDM4E 3586/4885RAB9A 1132/4885 |
| US-20220009930-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | UQCRB, CYP3A4, H1-4 | SMN1; SMN2 4439/4885KDM4E 542/4885RAB9A 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.