Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20066503 | 0.86 | PLK1 (0.53) | KMT2ATAS1R3TAS1R1CYP4A11LOXL2 | |
| SCHEMBL8133026 | 0.79 | ADRB2 (0.46) | ADRB2ADRB1ADRB3HPGDSMN1; SMN2 | |
| SCHEMBL18082660 | 0.79 | PLK1 (0.56) | ADRB2ADRB1ADRB3SMN1; SMN2ALDH1A1 | |
| SCHEMBL27843891 | 0.79 | ADRB2 (0.45) | ADRB2ADRB1ADRB3HPGDSMN1; SMN2 | |
| SCHEMBL10538105 | 0.79 | L3MBTL1 (0.51) | HPGDSMN1; SMN2SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13703211 | 0.79 | SLC7A5 (0.51) | SMN1; SMN2SLC6A3TDP1PKMALDH1A1 | |
| SCHEMBL7735376 | 0.78 | KMT2A (0.53) | SMN1; SMN2KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL16453798 | 0.78 | KMT2A (0.53) | SMN1; SMN2KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL12158530 | 0.77 | SLC6A2 (0.49) | ADRB2ADRB1ADRB3HPGDSMN1; SMN2 | |
| SCHEMBL17290731 | 0.76 | PLK1 (0.53) | HPGDSMN1; SMN2KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| EP-3287453-A1 | IMIDAZOLE COMPOUND | Medshine Discovery Inc. (CN) | 2018-02-28 | — | — | EP | disclosed |
| EP-3287453-A1 | IMIDAZOLE COMPOUND | Medshine Discovery Inc. (CN) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016169514-A1 | IMIDAZOLE COMPOUND | 广东众生药业股份有限公司 | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MAPT, SLC10A2, SLC5A11 | ADRB2 577/4885ADRB1 888/4885ADRB3 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.