Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180505 | 0.86 | ADRB2 (0.49) | PLK1ALDH1A1TDP1L3MBTL1TAS1R3 | |
| SCHEMBL19520440 | 0.82 | ALDH1A1 (0.55) | PLK1ALDH1A1TDP1CHRM2CYP2D6 | |
| SCHEMBL18082660 | 0.79 | PLK1 (0.56) | PLK1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL27843891 | 0.79 | ADRB2 (0.45) | ALDH1A1L3MBTL1LMNAKMT2AMEN1 | |
| SCHEMBL10538105 | 0.79 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1KCNH2LMNANPC1 | |
| SCHEMBL13703211 | 0.79 | SLC7A5 (0.51) | ALDH1A1TDP1CHRM2DRD3KCNH2 | |
| SCHEMBL16453798 | 0.78 | KMT2A (0.53) | ALDH1A1TDP1L3MBTL1ADRA2BKCNH2 | |
| SCHEMBL7735376 | 0.78 | KMT2A (0.53) | ALDH1A1TDP1L3MBTL1ADRA2BKCNH2 | |
| SCHEMBL3129690 | 0.77 | ALDH1A1 (0.59) | PLK1ALDH1A1TDP1CHRM2CYP2D6 | |
| SCHEMBL17290731 | 0.76 | PLK1 (0.53) | PLK1ALDH1A1TAS1R3TAS1R1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MAPT, SLC10A2, SLC5A11 | PLK1 171/4885ALDH1A1 1316/4885TDP1 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.