Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633423 | 0.85 | TUBB1 (0.33) | TUBB1ALDH1A1L3MBTL1NFE2L2LMNA | |
| SCHEMBL27665453 | 0.82 | TUBB1 (0.35) | TUBB1NFE2L2LMNAMAPK1HTT | |
| SCHEMBL11016571 | 0.77 | RAB9A (0.34) | TUBB1ALDH1A1NFE2L2LMNAMAPK1 | |
| SCHEMBL4300328 | 0.75 | HTR2A (0.41) | TUBB1ALDH1A1NFE2L2LMNAMAPK1 | |
| SCHEMBL30829726 | 0.75 | HTR2A (0.41) | TUBB1ALDH1A1NFE2L2LMNAMAPK1 | |
| SCHEMBL27759581 | 0.74 | TUBB1 (0.33) | TUBB1NFE2L2LMNAMAPK1HTT | |
| SCHEMBL10578058 | 0.74 | TUBB1 (0.35) | TUBB1ALDH1A1NFE2L2LMNAMAPK1 | |
| SCHEMBL13578451 | 0.74 | TUBB1 (0.44) | TUBB1ALDH1A1L3MBTL1CHUKPRKD3 | |
| SCHEMBL27553534 | 0.73 | CYP17A1 (0.35) | TUBB1ALDH1A1NFE2L2LMNAMAPK1 | |
| SCHEMBL27632292 | 0.73 | TDP1 (0.46) | ALDH1A1L3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-10590081-B2 | Guanidine compounds and use thereof | IMMUNOMET THERAPEUTICS INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| EP-3288918-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | Immunomet Therapeutics Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016175357-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| CN-100349864-C | Treating syndrome X with substituted tetralins and indanes | JANSSEN PHARMACEUTICA NV (BE) | 2007-11-21 | — | — | CN | disclosed |
| CN-1897936-A | Cyclic guanidines, compositions containing such compounds and methods of use | MERCK & CO INC (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1726188-A | Treatment of syndrome X with substituted 1,2,3, 4-tetrahydronaphthalenes and indanes | JANSSEN PHARMACEUTICA NV (BE) | 2006-01-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | TUBB1 3652/4885ALDH1A1 1446/4885L3MBTL1 2724/4885 |
| US-10590081-B2 | Guanidine compounds and use thereof | PC, TFAM, PCK2 | TUBB1 3652/4885ALDH1A1 1446/4885L3MBTL1 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.