Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821168 | 0.84 | MAPT (0.49) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL163754 | 0.84 | MAPT (0.49) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL1820200 | 0.84 | ACACB (0.38) | MAPTKDM4ESMN1; SMN2MAPK1ACACB | |
| SCHEMBL4857099 | 0.82 | MAPT (0.52) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5170201 | 0.81 | MAPT (0.42) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4649497 | 0.80 | KDM4E (0.46) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4649145 | 0.80 | LMNA (0.49) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8358624 | 0.80 | GRM5 (0.51) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL5172544 | 0.77 | APP (0.41) | MEN1KMT2AACACBALDH1A1 | |
| SCHEMBL1819985 | 0.77 | MCHR1 (0.48) | ACACBCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494408-A1 | PHOTOCHROMIC MATERIALS | Transitions Optical, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053615-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2011-05-05 | — | — | WO | disclosed |
| EP-1776436-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006022825-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-02 | — | — | WO | disclosed |