Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 7/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818040 | 0.89 | FAAH (0.48) | MCHR1APPACACB | |
| SCHEMBL9942722 | 0.88 | APP (0.53) | MCHR1APPACACBAOC3TSHR | |
| SCHEMBL5172544 | 0.86 | APP (0.41) | APPACACBNR1I2ALDH1A1RECQL | |
| SCHEMBL5024474 | 0.85 | ALDH1A1 (0.53) | APPNR1I2TSHRALDH1A1RECQL | |
| SCHEMBL3924311 | 0.81 | APP (0.46) | APPACACBAOC3CYP2C9ALDH1A1 | |
| SCHEMBL23572596 | 0.80 | APP (0.49) | APPACACBALDH1A1 | |
| SCHEMBL22122696 | 0.80 | KMT2A (0.47) | APPACACBTSHRALDH1A1 | |
| SCHEMBL2683955 | 0.80 | KMT2A (0.47) | APPACACBTSHRALDH1A1 | |
| SCHEMBL2685285 | 0.80 | APP (0.49) | APPACACBALDH1A1 | |
| SCHEMBL77535 | 0.78 | ALDH1A1 (0.60) | APPNR1I2CYP2C9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494408-A1 | PHOTOCHROMIC MATERIALS | Transitions Optical, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053615-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2011-05-05 | — | — | WO | disclosed |