Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627668 | 1.00 | KDM1A (0.41) | KDM1AKDM1BSLC6A4CHRNB2CHRNA4 | |
| SCHEMBL16905177 | 0.91 | PTGDR (0.40) | KDM1AKDM1BSLC6A4NOS3NOS1 | |
| SCHEMBL5769118 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16905434 | 0.80 | KDM1A (0.40) | KDM1AKDM1BSLC6A4CHRNB2CHRNA4 | |
| SCHEMBL30014308 | 0.80 | KDM1A (0.40) | KDM1AKDM1BSLC6A4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6393568 | 0.79 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL15416743 | 0.75 | CHRNB2 (0.34) | KDM1AKDM1BSLC6A4CHRNB2CHRNA4 | |
| SCHEMBL3404594 | 0.74 | HSP90AA1 (0.39) | KDM1AKDM1BSLC6A4NOS3NOS1 | |
| SCHEMBL19295072 | 0.74 | HSD17B1 (0.34) | KDM1ASLC6A4 | |
| SCHEMBL451775 | 0.73 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3RARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642258-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-04-03 | — | — | EP | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11393988-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-07-19 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3424936-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |
| EP-3102650-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-08-29 | — | — | EP | disclosed |
| EP-3094638-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-3094638-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| WO-2014023377-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-02-13 | — | — | WO | disclosed |
| EP-1963251-B1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-15 | — | — | EP | disclosed |
| EP-2316814-A1 | Process for preparation of halogen substituted benzonorbornenes derivatives | Syngenta Participations AG (CH) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316813-A1 | Process for the preparation of amines | Syngenta Participations AG (CH) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316809-A1 | Process for the preparation of benzonorbornane derivatives | Syngenta Participations AG (CH) | 2011-05-04 | — | — | EP | disclosed |
| US-7781615-B2 | Process for the preparation of amines | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1963251-A2 | PROCESS FOR THE PREPARATION OF AMINES | Syngeta Participations AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007068417-A2 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-21 | — | — | WO | disclosed |
| US-4980509-A | Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics | SOCIETE ANONYME DITE: L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11393988-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | KDM1A 4098/4885KDM1B 3685/4885SLC6A4 2877/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | KDM1A 4098/4885KDM1B 3685/4885SLC6A4 2877/4885 |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | HRH3, PAH, C1R | KDM1A 272/4885KDM1B 161/4885SLC6A4 4435/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | KDM1A 3005/4885KDM1B 2965/4885SLC6A4 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.