Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036787 | 0.81 | — | — | |
| SCHEMBL25686596 | 0.81 | — | — | |
| SCHEMBL25686595 | 0.81 | — | — | |
| SCHEMBL92802 | 0.76 | NOS1 (0.46) | NOS1MAPKAPK2 | |
| SCHEMBL11884517 | 0.73 | GLA (0.36) | NOS1MAPKAPK2 | |
| SCHEMBL8251589 | 0.71 | — | — | |
| SCHEMBL17472507 | 0.71 | — | — | |
| SCHEMBL5768296 | 0.69 | — | — | |
| SCHEMBL4559467 | 0.69 | — | — | |
| SCHEMBL14314366 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160320402-A1 | HIGH-AFFINITY SMALL MOLECULE FORMYLPEPTIDE RECEPTOR LIGANDS FROM SCREENING OF COMBINATORIAL MIXTURE-BASED LIBRARIES | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160320402-A1 | HIGH-AFFINITY SMALL MOLECULE FORMYLPEPTIDE RECEPTOR LIGANDS FROM SCREENING OF COMBINATORIAL MIXTURE-BASED LIBRARIES | FPR2, FPR1, FPR3 | BRD4 1662/4885CREBBP 1404/4885NOS1 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.