Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18190999 | 0.99 | SCN5A (0.42) | SCN5ASCN9AKCNH2HRH3EPHX2 | |
| SCHEMBL14703144 | 0.88 | HRH3 (0.45) | SCN9AHRH3EPHX2NR1H4HTR2C | |
| SCHEMBL14703361 | 0.88 | HRH3 (0.47) | SCN9AHRH3EPHX2NR1H4HTR2C | |
| SCHEMBL14703251 | 0.87 | EPHX2 (0.47) | HRH3EPHX2NR1H4HTR2CNAMPT | |
| SCHEMBL14703473 | 0.85 | ALDH1A1 (0.51) | HRH3EPHX2NR1H4HTR2CNAMPT | |
| SCHEMBL17356945 | 0.83 | EPHX2 (0.43) | HRH3EPHX2NR1H4HTR2CNAMPT | |
| SCHEMBL20023235 | 0.83 | SCN3A (0.37) | SCN5ASCN9AKCNH2EPHX2TRPV1 | |
| SCHEMBL16692446 | 0.82 | EPHX2 (0.47) | EPHX2MAPT | |
| SCHEMBL18191042 | 0.82 | TGM2 (0.38) | FPR3FPR2SMN1; SMN2 | |
| SCHEMBL17356975 | 0.81 | HRH3 (0.39) | SCN9AHRH3EPHX2NR1H4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | claimed |
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| WO-2016175357-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | SCN5A 2478/4885SCN9A 3111/4885KCNH2 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.