Sugi Predict

Sugi Predict / Compounds / SCHEMBL1820187

SCHEMBL1820187

SCHEMBL1820187

Oc1ccc(C=Cc2ccc(O)c(O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 4/20 1.00
▸ NQO2 P16083 4/20 1.00
▸ CYP3A4 P08684 4/20 0.72
▸ ALDH1A1 P00352 4/20 0.72
▸ TP53 P04637 3/20 0.72
▸ CYP1A2 P05177 3/20 0.72
▸ CYP2C9 P11712 3/20 0.72
▸ HIF1A Q16665 3/20 0.72
▸ HSD17B10 Q99714 3/20 0.72
▸ KDM4E B2RXH2 3/20 0.72
▸ MEN1 O00255 3/20 0.72
▸ LMNA P02545 3/20 0.72
▸ MAPT P10636 3/20 0.72
▸ HPGD P15428 3/20 0.72
▸ KMT2A Q03164 3/20 0.72
▸ SMN1; SMN2 Q16637 3/20 0.72
▸ ALOX12 P18054 2/20 0.72
▸ PKM P14618 2/20 0.72
▸ ALOX15 P16050 2/20 0.72
▸ THPO P40225 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820186 1.00 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL27233582 1.00 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL10335571 0.93 LCK (0.94) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL1824176 0.90 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL31706727 0.90 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL1824175 0.90 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL30631591 0.90 LCK (1.00) LCKNQO2CYP3A4ALDH1A1TP53
SCHEMBL10021657 0.84 CYP2C9 (0.74) LCKNQO2CYP3A4ALDH1A1CYP2C9
(E)-3,4-Stilbendiol SCHEMBL1821396 0.84 LCK (0.77) LCKNQO2CYP3A4ALDH1A1TP53
(E)-3,4-Stilbendiol SCHEMBL1821395 0.84 LCK (0.77) LCKNQO2CYP3A4ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 — — EP claimed
CN-118401224-A Cosmetic or cosmeceutical product for skin care and improving skin condition 迈瑞维拓股份公司 2024-07-26 — — CN claimed
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 — — EP claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 — — WO claimed
EP-3654929-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2020-05-27 — — EP claimed
WO-2019016153-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2019-01-24 — — WO claimed
EP-2315583-B1 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2018-05-09 — — EP claimed
JP-2011528336-A — — 2011-11-17 — — JP claimed
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE PECHERE LAURENT 2011-07-28 — — US claimed
EP-2315583-A2 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE Yvery (FR) 2011-05-04 — — EP claimed
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene L'OREAL (FR) 2002-12-05 — — US claimed
EP-1234571-A1 Topical composition containing a hydroxystilbene and a polyol L'OREAL (FR) 2002-08-28 — — EP claimed
US-6440433-B1 TREATING MENOPAUSAL SKIN DISORDERS; APPLYING TOPICAL MIXTURE TO IMPART AGING RESISTANCE; ACTIVATING SKIN FIBROBLAST PROLIFERATION SOCIETE L'OREAL S.A. (FR) 2002-08-27 — — US claimed
EP-1068864-A1 Use of at least a hydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-01-17 — — EP claimed
EP-1064931-A1 Cosmetic composition containing at least an hydroxystilbene and ascorbic acid L'OREAL (FR) 2001-01-03 — — EP claimed
US-6147121-A TOPICALLY APPLYING HYDROXYSTILBENE DERIVATIVE TO TREAT SKIN AGING AND WRINKLES SOCIETE L'OREAL S.A. (FR) 2000-11-14 — — US claimed
US-6124364-A Desquamation/epidermal renewal of the skin and/or combating skin aging SOCIETE L'OREAL S.A. (FR) 2000-09-26 — — US claimed
EP-0953346-A1 Use of at least a hydroxystilbebe in a skin fortifying composition L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953344-A1 Use of at least one hydroxystilbene in a composition to stimulate desquamation of the skin and compositions containing it L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953345-A1 Use of at least a hydroxystilbene as an agent for decreasing micro-organism adhesion L'OREAL (FR) 1999-11-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE FABP2, SI, SLC10A2 LCK 3753/4885NQO2 1315/4885CYP3A4 92/4885
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene CYP8B1, HSD17B1, HSD11B1 LCK 3170/4885NQO2 3562/4885CYP3A4 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.