Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.77 |
| ▸ | NQO2 | P16083 | 4/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | HNF4A | P41235 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TTR | P02766 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (E)-3,4-Stilbendiol SCHEMBL1821396 | 1.00 | LCK (0.77) | LCKNQO2PTGS1PTPN1HNF4A | |
| SCHEMBL10335331 | 0.91 | LCK (0.64) | LCKNQO2PTGS1PTPN1HNF4A | |
| SCHEMBL10335332 | 0.91 | LCK (0.64) | LCKNQO2PTGS1PTPN1HNF4A | |
| SCHEMBL10335571 | 0.91 | LCK (0.94) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL1931423 | 0.88 | LCK (0.81) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL1824175 | 0.88 | LCK (1.00) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL30631591 | 0.88 | LCK (1.00) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL31706727 | 0.88 | LCK (1.00) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL1824176 | 0.88 | LCK (1.00) | LCKNQO2PTGS1PTPN1HSD17B10 | |
| SCHEMBL12866199 | 0.85 | LCK (0.61) | LCKNQO2PTGS1PTPN1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436538-A1 | COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION | Merryvital AG (CH) | 2024-10-02 | — | — | EP | claimed |
| EP-3654929-B1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | OREAL (FR) | 2024-05-29 | — | — | EP | claimed |
| WO-2023094852-A1 | COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION | MERRYVITAL AG (CH) | 2023-06-01 | — | — | WO | claimed |
| EP-3654929-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2020-05-27 | — | — | EP | claimed |
| WO-2019016153-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2019-01-24 | — | — | WO | claimed |
| EP-2315583-B1 | FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | YVERY (FR) | 2018-05-09 | — | — | EP | claimed |
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | claimed |
| JP-2011528336-A | — | — | 2011-11-17 | — | — | JP | claimed |
| US-20110184072-A1 | FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | PECHERE LAURENT | 2011-07-28 | — | — | US | claimed |
| EP-2315583-A2 | FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | Yvery (FR) | 2011-05-04 | — | — | EP | claimed |
| US-20020183400-A1 | Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene | L'OREAL (FR) | 2002-12-05 | — | — | US | claimed |
| EP-1234571-A1 | Topical composition containing a hydroxystilbene and a polyol | L'OREAL (FR) | 2002-08-28 | — | — | EP | claimed |
| US-6440433-B1 | TREATING MENOPAUSAL SKIN DISORDERS; APPLYING TOPICAL MIXTURE TO IMPART AGING RESISTANCE; ACTIVATING SKIN FIBROBLAST PROLIFERATION | SOCIETE L'OREAL S.A. (FR) | 2002-08-27 | — | — | US | claimed |
| EP-1068864-A1 | Use of at least a hydroxystilbene as a glycation inhibitor | L'OREAL (FR) | 2001-01-17 | — | — | EP | claimed |
| EP-1064931-A1 | Cosmetic composition containing at least an hydroxystilbene and ascorbic acid | L'OREAL (FR) | 2001-01-03 | — | — | EP | claimed |
| US-6147121-A | TOPICALLY APPLYING HYDROXYSTILBENE DERIVATIVE TO TREAT SKIN AGING AND WRINKLES | SOCIETE L'OREAL S.A. (FR) | 2000-11-14 | — | — | US | claimed |
| US-6124364-A | Desquamation/epidermal renewal of the skin and/or combating skin aging | SOCIETE L'OREAL S.A. (FR) | 2000-09-26 | — | — | US | claimed |
| EP-0953346-A1 | Use of at least a hydroxystilbebe in a skin fortifying composition | L'OREAL (FR) | 1999-11-03 | — | — | EP | claimed |
| EP-0953345-A1 | Use of at least a hydroxystilbene as an agent for decreasing micro-organism adhesion | L'OREAL (FR) | 1999-11-03 | — | — | EP | claimed |
| EP-0953344-A1 | Use of at least one hydroxystilbene in a composition to stimulate desquamation of the skin and compositions containing it | L'OREAL (FR) | 1999-11-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184072-A1 | FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | FABP2, SI, SLC10A2 | LCK 3753/4885NQO2 1315/4885PTGS1 453/4885 |
| US-20020183400-A1 | Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene | CYP8B1, HSD17B1, HSD11B1 | LCK 3170/4885NQO2 3562/4885PTGS1 157/4885 |
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | SIRT1, SIRT7, SIRT5 | LCK 4126/4885NQO2 445/4885PTGS1 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.