SCHEMBL1820656

SCHEMBL1820656

C=C(CC=C(CC)C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.38
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GRIK1 P39086 4/20 0.33
GRIK2 Q13002 3/20 0.33
FFAR3 O14843 1/20 0.32
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
ABAT P80404 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2879158 0.83 ALDH1A1 (0.34) ALDH1A1
SCHEMBL29548444 0.81 GRIK1 (0.44) TET2ALOX15HSD17B10GRIK1GRIK2
SCHEMBL6046879 0.80 APEX1 (0.38) TET2ALOX15HSD17B10GRIK1ALDH1A1
SCHEMBL8604104 0.79 FFAR3 (0.43) ALOX15GRIK1GRIK2FFAR3ALDH1A1
SCHEMBL11842601 0.79 FFAR3 (0.43) ALOX15GRIK1GRIK2FFAR3ALDH1A1
SCHEMBL9453790 0.79 AKR1B1 (0.42) ALOX15HSD17B10ALDH1A1TSHR
Methacrylic Acid SCHEMBL6560561 0.79 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9117550 0.77 FNTA (0.44) ALOX15HSD17B10ALDH1A1TSHR
SCHEMBL11190671 0.77 FNTA (0.44) ALOX15HSD17B10ALDH1A1TSHR
SCHEMBL9343451 0.77 FNTA (0.44) ALOX15HSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173284-A1 EFLORNITHINE AND SULINDAC, FIXED DOSE COMBINATION FORMULATION CANCER PREVENTION PHARMACEUTICALS, INC. (US) 2024-05-30 US claimed
US-20240091201-A1 FORMULATIONS OF DEFERASIROX AND METHODS OF MAKING THE SAME AustinPx, LLC (US) 2024-03-21 US claimed
US-11878005-B2 Formulations of deferasirox and methods of making the same AustinPx, LLC (US) 2024-01-23 US claimed
US-20230218533-A1 3D LASER SINTERING PROCESSES FOR IMPROVED DRUG DELIVERY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-07-13 US claimed
US-20230167181-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS OF MANUFACTURE USING THERMALLY CONDUCTIVE EXCIPIENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-06-01 US claimed
WO-2023086832-A1 METHODS OF PREPARING DOSAGE FORMS USING 3D PRINTING CONTAINING AMORPHOUS SOLID DISPERSIONS BOARD OF REGENTS, THE UNIVERSITY OFTEXAS SYSTEM (US) 2023-05-19 WO claimed
EP-4164618-A1 3D LASER SINTERING PROCESSES FOR IMPROVED DRUG DELIVERY Board of Regents, The University of Texas System (US) 2023-04-19 EP claimed
US-20220402884-A1 (S)-N-HYDROXY-2-(2-(4-METHOXYPHENYL)BUTANAMIDO)THIAZOLE-5-CARBOXAMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF TRANSLATIONAL DRUG DEVELOPMENT, LLC 2022-12-22 US claimed
US-11420947-B2 (S)-n-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide and pharmaceutically acceptable salts thereof TRANSLATIONAL DRUG DEVELOPMENT, LLC (US) 2022-08-23 US claimed
WO-2021252793-A1 3D LASER SINTERING PROCESSES FOR IMPROVED DRUG DELIVERY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-12-16 WO claimed
US-20140039031-A1 PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-B-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS Dispersol Technologies. LLC (US) 2014-02-06 US claimed
WO-2012116238-A1 PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS DISPERSOL TECHNOLOGIES, LLC (US) 2012-08-30 WO claimed
EP-2486918-A2 PHARMACEUTICAL COMPOSITION WITH BOTH IMMEDIATE AND EXTENDED RELEASE CHARACTERISTICS Yungjin Pharm. Co. Ltd. (KR) 2012-08-15 EP claimed
US-20110217374-A1 PHARMACEUTICAL COMPOSITION SIMULTANEOUSLY HAVING RAPID-ACTING PROPERTY AND LONG-ACTING PROPERTY YUNGJIN PHARM. CO., LTD. (KR) 2011-09-08 US claimed
US-6752953-B2 HEATING A CAPSULE FORMING COMPOSITION IN A MOLD, FOLLOWED BY INSERTING A PESTLE INTO THE MOLD TO COAT THE MELTED CAPSULE FORMING COMPOSITION ONTO THE PESTLE. YUNG SHIN PHARMACEUTICAL CO., LTD. (TW) 2004-06-22 US claimed
US-20030161872-A1 Capsule for holding liquid-containing compositions and method for making the same YUNG SHIN PHARMACEUTICAL INDUSTRIAL CO., LTD. (TW) 2003-08-28 US claimed
EP-1235556-A4 TASTE MASKING COATING COMPOSITIONS RANBAXY LAB LTD (IN) 2003-07-16 EP claimed
US-20030104047-A1 Method for manufacturing hard non-gelatin pharmaceutical capsules YUNG SHIN PHARMACEUTICAL INDUSTRIAL CO., LTD. (TW) 2003-06-05 US claimed
EP-1235556-A2 TASTE MASKING COATING COMPOSITIONS RANBAXY LABORATORIES, LTD. (IN) 2002-09-04 EP claimed
WO-2000056266-A2 TASTE MASKING COATING COMPOSITIONS RANBAXY LABORATORIES LIMITED (US) 2000-09-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240091201-A1 FORMULATIONS OF DEFERASIROX AND METHODS OF MAKING THE SAME FECH, PFKP, DUT TET2 199/4885ALOX15 188/4885HSD17B10 1493/4885
US-20030161872-A1 Capsule for holding liquid-containing compositions and method for making the same C5, RCC1, DEPTOR TET2 1605/4885ALOX15 134/4885HSD17B10 1390/4885
US-20220402884-A1 (S)-N-HYDROXY-2-(2-(4-METHOXYPHENYL)BUTANAMIDO)THIAZOLE-5-CARBOXAMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HDAC5, HDAC2, HDAC3 TET2 1348/4885ALOX15 4057/4885HSD17B10 163/4885
US-11878005-B2 Formulations of deferasirox and methods of making the same FECH, PFKP, DUT TET2 199/4885ALOX15 188/4885HSD17B10 1493/4885
US-11420947-B2 (S)-n-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide and pharmaceutically acceptable salts thereof HDAC5, HDAC2, HDAC3 TET2 1348/4885ALOX15 4057/4885HSD17B10 163/4885
US-20030104047-A1 Method for manufacturing hard non-gelatin pharmaceutical capsules PGA5, DSTN, RPS5 TET2 1281/4885ALOX15 1169/4885HSD17B10 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.