SCHEMBL1820814

SCHEMBL1820814

O=c1[nH]c(=S)c2ncn(OP(=O)(O)O)c2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.49
▸ PNP P00491 2/20 0.35
▸ TSHR P16473 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28335557 0.91 ALDH1A1 (0.44) ALDH1A1PNP
SCHEMBL28333212 0.88 ALDH1A1 (0.42) ALDH1A1PNP
SCHEMBL389888 0.87 PNP (0.46) ALDH1A1PNP
SCHEMBL29112126 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10
SCHEMBL6680764 0.72 HPRT1 (0.38) ALDH1A1PNPHSD17B10
SCHEMBL27952597 0.71 PNP (0.41) PNP
SCHEMBL15290224 0.71 ALDH1A1 (0.56) ALDH1A1PNPTSHRCYP2C19HSD17B10
SCHEMBL27277482 0.68 ALDH1A1 (0.52) ALDH1A1PNPTSHRCYP2C19HSD17B10
SCHEMBL7958461 0.68 ALDH1A1 (0.52) ALDH1A1TSHRCYP2C19HSD17B10
SCHEMBL9845196 0.66 ALDH1A1 (0.50) ALDH1A1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460229-B2 Recombinant arterivirus replicon systems and uses thereof Janssen Pharmaceuticals, Inc. (US) 2025-11-04 — — US disclosed
CN-110352247-B Compositions and methods for enhancing gene expression 杨森制药公司 2024-06-28 — — CN disclosed
US-20240209379-A1 COMPOSITIONS AND METHODS FOR ENHANCING GENE EXPRESSION Janssen Pharmaceuticals, Inc. 2024-06-27 — — US disclosed
EP-3548625-B1 COMPOSITIONS AND METHODS FOR ENHANCING GENE EXPRESSION JANSSEN PHARMACEUTICALS INC (US) 2024-06-26 — — EP disclosed
US-11845939-B2 Compositions and methods for enhancing gene expression Janssen Pharmaceuticals, Inc. (US) 2023-12-19 — — US disclosed
US-20230227850-A1 RECOMBINANT ARTERIVIRUS REPLICON SYSTEMS AND USES THEREOF Janssen Pharmaceuticals, Inc. 2023-07-20 — — US disclosed
US-11555205-B2 Recombinant arterivirus replicon systems and uses thereof Janssen Pharmaceuticals, Inc. (US) 2023-01-17 — — US disclosed
US-11219895-B2 Blood analysis cartridge KING ABDULAZIZ UNIVERSITY (SA) 2022-01-11 — — US disclosed
US-20210308674-A1 BLOOD ANALYSIS CARTRIDGE KING ABDULAZIZ UNIVERSITY (SA) 2021-10-07 — — US disclosed
US-20210001333-A1 MICROFLUIDIC DEVICE FOR MEASURING THE ENZYMATIC ACTIVITY OF THIOPURIN S-METHYLTRANSFERASE KING ABDULAZIZ UNIVERSITY (SA) 2021-01-07 — — US disclosed
WO-1996021007-A2 BACTERIOPHAGE-MEDIATED GENE TRANSFER SYSTEMS CAPABLE OF TRANSFECTING EUKARYOTIC CELLS CHIRON VIAGENE, INC. (US) 1996-07-11 — — WO disclosed
WO-1996021036-A2 NUCLEIC ACID CONDENSING AGENTS WITH REDUCED IMMUNOGENICITY CHIRON VIAGENE, INC. (US) 1996-07-11 — — WO disclosed
WO-1996020732-A2 NON-TRAUMATIC ADMINISTRATION OF GENE DELIVERY VEHICLES CHIRON CORPORATION (US) 1996-07-11 — — WO disclosed
EP-0716148-A2 Recombinant alphavirus vectors CHIRON VIAGENE, INC. (US) 1996-06-12 — — EP disclosed
WO-1996017072-A2 RECOMBINANT ALPHAVIRUS VECTORS CHIRON VIAGENE, INC. (US) 1996-06-06 — — WO disclosed
EP-0711829-A2 Recombinant alphavirus vectors CHIRON VIAGENE, INC. (US) 1996-05-15 — — EP disclosed
EP-0694070-A1 RECOMBINANT ALPHAVIRUS VECTORS CHIRON CORPORATION (US) 1996-01-31 — — EP disclosed
WO-1995024928-A2 HEPARIN-BINDING GROWTH FACTORS FOR GENE THERAPY AND ANTERIOR EYE DISORDERS PRIZM PHARMACEUTICALS, INC. (US) 1995-09-21 — — WO disclosed
WO-1995014091-A2 COMPOSITIONS AND METHODS FOR UTILIZING CONDITIONALLY LETHAL GENES CHIRON VIAGENE, INC. (US) 1995-05-26 — — WO disclosed
WO-1995007994-A2 RECOMBINANT ALPHAVIRUS VECTORS VIAGENE, INC. (US) 1995-03-23 — — WO disclosed
Send feedback