Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831055 | 0.87 | SORT1 (0.77) | SORT1HPGDRAB9ALMNAKDM4E | |
| SCHEMBL27660016 | 0.85 | HPGD (0.64) | SORT1HPGDRAB9ALMNAALDH1A1 | |
| SCHEMBL740129 | 0.81 | HPGD (0.66) | HPGDRAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL1820673 | 0.81 | HPGD (0.68) | SORT1HPGDLMNAALDH1A1KMT2A | |
| SCHEMBL18007328 | 0.81 | SORT1 (0.53) | SORT1HPGDRAB9ALMNAKDM4E | |
| SCHEMBL13820259 | 0.80 | RAB9A (0.58) | HPGDRAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30417260 | 0.79 | SORT1 (0.67) | SORT1RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL1818730 | 0.79 | SORT1 (0.67) | SORT1RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL4907748 | 0.78 | SORT1 (0.58) | SORT1HPGDRAB9ALMNAKDM4E | |
| SCHEMBL15903134 | 0.76 | SORT1 (0.91) | SORT1HPGDRAB9ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8710242-B2 | Haloalky -substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | CRYAA, ACLY, CRYZ | SORT1 4748/4885HPGD 3707/4885RAB9A 152/4885 |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | CRYAA, ACLY, CRYZ | SORT1 4748/4885HPGD 3707/4885RAB9A 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.