Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18017404 | 0.88 | — | — | |
| SCHEMBL21278569 | 0.80 | — | — | |
| SCHEMBL18210797 | 0.79 | — | — | |
| SCHEMBL18210796 | 0.74 | IDH1 (0.35) | — | |
| SCHEMBL21278563 | 0.70 | — | — | |
| SCHEMBL16751966 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL13859196 | 0.67 | CHRNB2 (0.33) | — | |
| SCHEMBL12302670 | 0.65 | MEN1 (0.41) | — | |
| SCHEMBL427869 | 0.64 | HCAR2 (0.47) | SLC22A12 | |
| SCHEMBL12190544 | 0.63 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |