Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 8/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12190544 | 0.83 | LMNA (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL30388361 | 0.82 | ALDH1A1 (0.39) | P2RX7ALDH1A1 | |
| SCHEMBL2420286 | 0.82 | ALDH1A1 (0.39) | P2RX7ALDH1A1 | |
| SCHEMBL1549298 | 0.82 | ALDH1A1 (0.39) | P2RX7ALDH1A1 | |
| SCHEMBL2420288 | 0.82 | ALDH1A1 (0.39) | P2RX7ALDH1A1 | |
| SCHEMBL24122821 | 0.78 | CYP11B2 (0.37) | P2RX7 | |
| SCHEMBL22978658 | 0.78 | S100A9 (0.41) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL22990521 | 0.78 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL29698274 | 0.78 | S100A9 (0.41) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL10325651 | 0.78 | CHRNB2 (0.33) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709983-B1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-18 | — | — | EP | disclosed |
| EP-2709983-B1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-18 | — | — | EP | disclosed |
| US-8895587-B2 | Insecticidal compounds based on arylthioacetamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-25 | — | — | US | disclosed |
| US-8895587-B2 | Insecticidal compounds based on arylthioacetamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-25 | — | — | US | disclosed |
| US-8895587-B2 | Insecticidal compounds based on arylthioacetamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-25 | — | — | US | disclosed |
| US-20140107161-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| US-20140107161-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| US-20140107161-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| EP-2709983-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012156400-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012156400-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107161-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | NAT1, ACHE, CHRM1 | CHRNB2 1427/4885CHRNA4 965/4885CHRNB4 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.