Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | IDH2 | P48735 | 4/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | KCNT1 | Q5JUK3 | 4/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KCNMB1 | Q16558 | 1/20 | 0.33 |
| ▸ | KCNT2 | Q6UVM3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18577 | 0.76 | IDH1 (0.39) | IDH1IDH2KCNT1KDM4ENPC1 | |
| SCHEMBL2334760 | 0.73 | NPSR1 (0.42) | P2RX7ADRB1KDM4ENPC1RAB9A | |
| SCHEMBL18484 | 0.71 | CA2 (0.38) | KCNT1KDM4EPTGS2 | |
| SCHEMBL18781 | 0.69 | ALDH1A1 (0.38) | IDH1IDH2ADRB1HDAC4 | |
| SCHEMBL22271284 | 0.67 | IDH1 (0.50) | P2RX7IDH1IDH2MBOAT4ADRB1 | |
| SCHEMBL16986457 | 0.66 | IDH1 (0.38) | P2RX7IDH1IDH2KCNT1ADRB1 | |
| SCHEMBL9771829 | 0.65 | NPC1 (0.44) | KDM4ENPC1RAB9A | |
| SCHEMBL22637946 | 0.65 | IDH1 (0.45) | IDH1IDH2KCNT1KCNQ1KCNH2 | |
| SCHEMBL22637944 | 0.65 | IDH1 (0.45) | IDH1IDH2KCNT1KCNQ1KCNH2 | |
| SCHEMBL22637369 | 0.64 | KCNT1 (0.53) | KCNT1KCNQ1KCNH2CACNA1CSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |