Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212282 | 0.87 | MGMT (0.40) | HPGDNPSR1MGLL | |
| SCHEMBL18212279 | 0.78 | GAA (0.39) | — | |
| SCHEMBL16307843 | 0.72 | IDUA (0.36) | HPGDNPSR1MGLL | |
| SCHEMBL17262434 | 0.70 | MGMT (0.40) | MGLL | |
| SCHEMBL25495612 | 0.69 | MGMT (0.42) | MGLL | |
| SCHEMBL14499669 | 0.67 | HPGD (0.50) | HPGDNPSR1 | |
| SCHEMBL30458078 | 0.66 | MGMT (0.42) | MGLL | |
| SCHEMBL30459733 | 0.66 | MGMT (0.39) | MGLL | |
| SCHEMBL29199650 | 0.66 | HPGD (0.49) | HPGDNPSR1 | |
| SCHEMBL30455579 | 0.66 | MGMT (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326266-A1 | Chemically-Locked Bispecific Antibodies | SORRENTO THERAPEUTICS, INC. (US) | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326266-A1 | Chemically-Locked Bispecific Antibodies | FCGR3B, FCGR2A, FCGR1A | HPGD 4146/4885NPSR1 3249/4885MGLL 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.