SCHEMBL18213657

SCHEMBL18213657

CN(C)c1ccc2c(c1)Oc1cc(N(C)C)ccc1C2c1ccccc1CN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.47
LMNA P02545 5/20 0.47
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPC1 O15118 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HTT P42858 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
GAA P10253 3/20 0.41
TSHR P16473 3/20 0.41
USP2 O75604 3/20 0.41
TP53 P04637 2/20 0.41
ALOX15 P16050 2/20 0.41
MAPK1 P28482 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
ALDH1A1 P00352 2/20 0.38
TUBB4A P04350 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18213652 0.87 LMNA (0.49) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL3896874 0.79 LMNA (0.46) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL18213654 0.79 MEN1 (0.44) LMNAMAPTSMN1; SMN2NPC1MEN1
SCHEMBL9626207 0.77 NPSR1 (0.51) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL28608473 0.75 CYP2C9 (0.64) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL18179775 0.74 MEN1 (0.43) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL8778242 0.73 ALOX15 (0.47) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL16547109 0.72 TSHR (0.42) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL5007875 0.72 LMNA (0.62) NPSR1LMNAMAPTSMN1; SMN2TDP1
SCHEMBL5010108 0.71 NPSR1 (0.41) NPSR1LMNAMAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-20160327863-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2016-11-10 US disclosed
US-20160327863-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2016-11-10 US disclosed