SCHEMBL18216

SCHEMBL18216

C/C(=N\OCc1cccc(C)c1)c1ccc(Cl)c(CN(C)C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
PPARG P37231 10/20 0.45
PPARA Q07869 8/20 0.45
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41
MAOB P27338 2/20 0.41
HSP90AA1 P07900 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40
CTBP2 P56545 1/20 0.39
NR1H4 Q96RI1 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18217 1.00 NPC1 (0.52) NPC1RAB9APPARGPPARAKDM4E
SCHEMBL26318 0.84 NPC1 (0.53) NPC1RAB9APPARGPPARAMAOB
SCHEMBL26317 0.84 NPC1 (0.53) NPC1RAB9APPARGPPARAMAOB
SCHEMBL25344075 0.82 NPC1 (0.50) NPC1RAB9APPARGPPARAMAOB
SCHEMBL337620 0.82 NPC1 (0.41) NPC1RAB9APPARGPPARANR1H4
SCHEMBL1138229 0.82 NPC1 (0.41) NPC1RAB9APPARGPPARANR1H4
SCHEMBL166029 0.82 NPC1 (0.41) NPC1RAB9APPARGPPARANR1H4
SCHEMBL18243 0.82 NPC1 (0.49) NPC1RAB9APPARGPPARAMAOB
SCHEMBL3236733 0.82 NPC1 (0.49) NPC1RAB9APPARGPPARAMAOB
SCHEMBL19566191 0.81 NPC1 (0.48) NPC1RAB9APPARGPPARAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646109-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS Invaio Sciences, Inc. (US) 2025-11-12 EP claimed
WO-2024168193-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS INVAIO SCIENCES, INC. (US) 2024-08-15 WO claimed
US-20240141370-A1 AGRICULTURAL COMPOSITIONS AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2024-05-02 US claimed
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
US-20220064661-A1 AGRICULTURAL COMPOSITIONS AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-03-03 US claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-2418944-B1 METHOD FOR COMBATING HARMFUL FUNGI BASF SE (DE) 2017-07-26 EP claimed
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-9232785-B2 Method for reducing sunburn damage in plants BASF SE (DE) 2016-01-12 US claimed
EP-2319320-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-11 EP claimed
EP-2319319-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-11 EP claimed
EP-2306832-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2011-04-13 EP claimed
WO-2011036111-A2 METHOD FOR REDUCING PISTILLATE FLOWER ABORTION IN PLANTS BASF SE (DE) 2011-03-31 WO claimed
WO-2011026796-A1 SYNERGISTIC FUNGICIDAL MIXTURES COMPRISING LACTYLATES AND METHOD FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2011-03-10 WO claimed
EP-2292098-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP claimed
EP-2292099-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP claimed
WO-2011012458-A1 A METHOD FOR INCREASING THE LEVEL OF FREE AMINO ACIDS IN STORAGE TISSUES OF PERENNIAL PLANTS BASF SE (DE) 2011-02-03 WO claimed
US-20100273649-A1 Fungicidal Mixtures III BASF SE (DE) 2010-10-28 US claimed
EP-1942737-B1 METHOD OF INDUCING RESISTANCE TO HARMFUL FUNGI BASF SE (DE) 2010-03-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE BTF3, MYB, AGXT NPC1 4630/4885RAB9A 2307/4885PPARG 1966/4885
US-20100273649-A1 Fungicidal Mixtures III CBR3, CBR1, NOX3 NPC1 993/4885RAB9A 1561/4885PPARG 2657/4885
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC NPC1 4818/4885RAB9A 4301/4885PPARG 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.