SCHEMBL26318

SCHEMBL26318

CC(=NOCc1cccc(C)c1)c1ccc(Cl)c(CNC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
PPARG P37231 8/20 0.46
PPARA Q07869 6/20 0.46
MAOB P27338 2/20 0.42
S1PR1 P21453 4/20 0.41
S1PR3 Q99500 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HPGD P15428 1/20 0.41
CTSB P07858 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26317 1.00 NPC1 (0.53) NPC1RAB9APPARGPPARAMAOB
SCHEMBL4667807 0.93 NPC1 (0.48) NPC1RAB9APPARGPPARAMAOB
SCHEMBL3236733 0.93 NPC1 (0.49) NPC1RAB9APPARGPPARAMAOB
SCHEMBL18243 0.93 NPC1 (0.49) NPC1RAB9APPARGPPARAMAOB
SCHEMBL18217 0.84 NPC1 (0.52) NPC1RAB9APPARGPPARAMAOB
SCHEMBL18216 0.84 NPC1 (0.52) NPC1RAB9APPARGPPARAMAOB
SCHEMBL25344075 0.83 NPC1 (0.50) NPC1RAB9APPARGPPARAMAOB
SCHEMBL2778024 0.82 NPC1 (0.41) NPC1RAB9APPARGPPARAS1PR1
SCHEMBL19566191 0.82 NPC1 (0.48) NPC1RAB9APPARGPPARAMAOB
SCHEMBL2744761 0.82 NPC1 (0.41) NPC1RAB9APPARGPPARAS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3381289-B1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BAYER CROPSCIENCE LP (US) 2021-05-05 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
US-20200146288-A1 COMBINATION OF PYROGLUTAMIC ACID AND A STROBILURIN FUNGICIDE FOR IMPROVED PLANT HEALTH EFFECTS GLAS AMERICAS LLC 2020-05-14 US claimed
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP claimed
EP-3510869-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2019-07-17 EP claimed
EP-2427062-B1 A METHOD FOR INCREASING THE CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BAYER CROPSCIENCE LP (US) 2019-01-16 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP claimed
US-20180007908-A1 Pesticidal Mixtures BASF SE (DE) 2018-01-11 US claimed
EP-1912504-A1 METHOD FOR CONTROLLING RUST INFECTIONS IN LEGUMINOUS PLANTS BASF SE (DE) 2008-04-23 EP claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
US-20080076747-A1 Fungicidal Mixtures BASF AKTIENGESELLSCHAFT (DE) 2008-03-27 US claimed
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens BASF AKTIENGESELLSCHAFT (DE) 2008-02-21 US claimed
WO-2007128756-A1 USE OF ARYLCARBOXYLIC ACID BIPHENYLAMIDES FOR SEED TREATMENT BASF SE (DE) 2007-11-15 WO claimed
WO-2007104660-A2 METHOD FOR IMPROVING THE TOLERANCE OF PLANTS TO CHILLING TEMPERATURES AND/OR FROST BASF SE (DE) 2007-09-20 WO claimed
WO-2007048735-A2 METHOD OF INDUCING RESISTANCE TO HARMFUL FUNGI BASF SE (DE) 2007-05-03 WO claimed
WO-2007017231-A1 USE OF ARYLANILIDES FOR SEED TREATMENT BASF AKTIENGESELLSCHAFT (DE) 2007-02-15 WO claimed
WO-2007017409-A1 METHOD FOR CONTROLLING RUST INFECTIONS IN LEGUMINOUS PLANTS BASF SE (DE) 2007-02-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200146288-A1 COMBINATION OF PYROGLUTAMIC ACID AND A STROBILURIN FUNGICIDE FOR IMPROVED PLANT HEALTH EFFECTS GLO1, PGAM1, GGH NPC1 4283/4885RAB9A 3345/4885PPARG 308/4885
US-20080076747-A1 Fungicidal Mixtures ERG28, CYP51A1, CASP7 NPC1 1130/4885RAB9A 1167/4885PPARG 4236/4885
US-20180007908-A1 Pesticidal Mixtures PTMS, THOP1, MLN NPC1 4658/4885RAB9A 2723/4885PPARG 3064/4885
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens DDT, CYP4X1, STS NPC1 3820/4885RAB9A 3048/4885PPARG 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.