Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18217033 | 0.85 | RORC (0.30) | RORC | |
| SCHEMBL18217031 | 0.82 | RORC (0.33) | RORC | |
| SCHEMBL18217052 | 0.75 | HDAC9 (0.34) | — | |
| SCHEMBL19256651 | 0.69 | HDAC8 (0.40) | AADAT | |
| SCHEMBL12250991 | 0.69 | HDAC8 (0.43) | AADAT | |
| SCHEMBL19132759 | 0.68 | PLK1 (0.30) | RORC | |
| SCHEMBL19132760 | 0.65 | RORC (0.33) | RORC | |
| SCHEMBL16210393 | 0.65 | HTR2C (0.42) | AADAT | |
| SCHEMBL24817957 | 0.64 | OGA (0.36) | AADAT | |
| SCHEMBL21672755 | 0.64 | AADAT (0.33) | AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160326104-A1 | CYCLOHEXYL SULFONE ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326104-A1 | CYCLOHEXYL SULFONE ROR GAMMA MODULATORS | RORB, RORC, RORA | RORC 2/4885AADAT 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.