Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18217053 | 0.84 | HTT (0.39) | HDAC9KMT2A | |
| SCHEMBL18217052 | 0.82 | HDAC9 (0.34) | HDAC9KMT2A | |
| SCHEMBL18217010 | 0.82 | RORC (0.34) | RORC | |
| SCHEMBL18217033 | 0.82 | RORC (0.30) | RORC | |
| SCHEMBL18217050 | 0.75 | OGA (0.39) | HDAC9 | |
| SCHEMBL16888281 | 0.75 | RORC (0.35) | RORCHDAC9KMT2A | |
| SCHEMBL19132834 | 0.74 | RORC (0.36) | RORC | |
| SCHEMBL19132763 | 0.73 | RORC (0.36) | RORCHDAC9KMT2A | |
| SCHEMBL19132760 | 0.70 | RORC (0.33) | RORCHDAC9 | |
| SCHEMBL19132871 | 0.69 | RORC (0.40) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160326104-A1 | CYCLOHEXYL SULFONE ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326104-A1 | CYCLOHEXYL SULFONE ROR GAMMA MODULATORS | RORB, RORC, RORA | RORC 2/4885HDAC9 474/4885KMT2A 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.