Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL812668 | 0.84 | HTR2A (0.40) | SIGMAR1RETHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6908577 | 0.82 | HTR2A (0.39) | SIGMAR1RETHTR6HTR2A | |
| Fluoride Ion SCHEMBL5183634 | 0.80 | HTR2A (0.40) | SIGMAR1RETHTR6HTR2A | |
| Bromide SCHEMBL6440191 | 0.80 | HTR2A (0.45) | SIGMAR1RETHTR6HTR2A | |
| SCHEMBL7107703 | 0.78 | HTR2A (0.36) | SIGMAR1RETHTR6HTR2A | |
| SCHEMBL3793472 | 0.78 | SIGMAR1 (0.33) | SIGMAR1RETHTR6HTR2A | |
| Ethylbenzene SCHEMBL6930967 | 0.73 | TP53 (0.47) | SIGMAR1RETHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6897360 | 0.72 | HTR6 (0.33) | SIGMAR1HTR6HTR2A | |
| Phenol SCHEMBL4827336 | 0.72 | HTR6 (0.38) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6559467 | 0.71 | HTR2A (0.38) | SIGMAR1RETHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291445-B1 | PROCESSES TO CONTROL FOULING AND IMPROVE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4223814-A2 | POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME | Honeywell International Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-2961782-B1 | POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME | HONEYWELL INT INC (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20220403129-A1 | POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME | HONEYWELL INTERNATIONAL INC. (US) | 2022-12-22 | — | — | US | disclosed |
| US-20220056252-A1 | CROSS-LINKED FOAMS MADE FROM INTERPOLYMERS OF ETHYLENE/ALPHA-OLEFINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-02-24 | — | — | US | disclosed |
| US-20210283886-A1 | MULTILAYER FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-09-16 | — | — | US | disclosed |
| EP-2527375-B1 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-2094739-B1 | POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-3549960-B1 | PROCESS FOR POLYMERIZING AN OLEFIN MONOMER AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-3216899-B1 | A FIBER COMPRISING A LOW CRYSTALLINITY POLYMER AND A HIGH CRYSTALLINITY POLYMER | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20060199930-A1 | Ethylene/alpha-olefins block interpolymers | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199887-A1 | Filled polymer compositions made from interpolymers of ethylene/a-olefins and uses thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199911-A1 | Cap liners, closures and gaskets from multi-block polymers | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199907-A1 | Compositions of ethylene/alpha-olefin multi-block interpolymer for elastic films and laminates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199906-A1 | Polymer blends from interpolymers of ethylene/alpha-olefin with improved compatibility | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199931-A1 | Fibers made from copolymers of ethylene/alpha-olefins | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199912-A1 | Compositions of ethylene/alpha-olefin multi-block interpolymer suitable for films | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199910-A1 | Thermoplastic vulcanizate comprising interpolymers of ethylene alpha-olefins | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-20060199905-A1 | Interpolymers of ethylene/a-olefins blends and profiles and gaskets made therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-07 | — | — | US | disclosed |
| WO-2005090427-A2 | CATALYST COMPOSITION COMPRISING SHUTTLING AGENT FOR ETHYLENE MULTI-BLOCK COPOLYMER FORMATION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-29 | — | — | WO | disclosed |