Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL5183634 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL812668 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6908577 | 0.93 | HTR2A (0.39) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| SCHEMBL7107703 | 0.89 | HTR2A (0.36) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Phenol SCHEMBL4827336 | 0.86 | HTR6 (0.38) | HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6897360 | 0.82 | HTR6 (0.33) | HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL182284 | 0.80 | SIGMAR1 (0.32) | HTR2AHTR6RETSIGMAR1 | |
| Ethylbenzene SCHEMBL6930967 | 0.80 | TP53 (0.47) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL5569257 | 0.78 | GPR3 (0.40) | HTR2AHTR6KCNH2BRD4CCL2 | |
| Hydrochloric Acid SCHEMBL6559467 | 0.77 | HTR2A (0.38) | HTR2AHTR6CYP2D6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509060-A | Metallocene compound, catalyst composite containing metallocene compound and olefin polymerization method using metallocene compound | DAELIM IND CO LTD | 2014-01-15 | — | — | CN | disclosed |
| US-6894120-B2 | Ethylene copolymer composition | MITSUI CHEMICALS, INC. (JP) | 2005-05-17 | — | — | US | disclosed |
| EP-0754731-B2 | Polyamide resin composition | MITSUI CHEMICALS INC (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-20040210004-A1 | Ethylene copolymer composition | TAKAHASHI MAMORU (JP) | 2004-10-21 | — | — | US | disclosed |
| US-6288193-B1 | Ethylene-based polymer | SUMITOMO CHEMICAL CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0668323-B1 | POLYAMIDE RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 1998-06-03 | — | — | EP | disclosed |