Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL812668 | 0.87 | HTR2A (0.40) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6908577 | 0.85 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| Bromide SCHEMBL6440191 | 0.82 | HTR2A (0.45) | HTR6HTR2ASIGMAR1 | |
| Fluoride Ion SCHEMBL5183634 | 0.82 | HTR2A (0.40) | HTR6HTR2ASIGMAR1 | |
| Phenol SCHEMBL4827336 | 0.78 | HTR6 (0.38) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL7107703 | 0.77 | HTR2A (0.36) | HTR6HTR2ASIGMAR1 | |
| Ethylbenzene SCHEMBL6930967 | 0.76 | TP53 (0.47) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL182284 | 0.72 | SIGMAR1 (0.32) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6559467 | 0.70 | HTR2A (0.38) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6903962 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373334-A1 | ETHYLENE POLYMERIZATION PROCESS | Equistar Chemicals, LP (US) | 2004-01-02 | — | — | EP | disclosed |
| US-6664349-B2 | Using coordination polymerization catalyst | EQUISTAR CHEMICALS, LP | 2003-12-16 | — | — | US | disclosed |
| US-6583240-B2 | In the presence of an activator and a Group 4 metal catalyst having at least one boraaryl ligand; wherein the catalyst is alkylated iwth triisobutyl aluminum; polyethylene with higher long chain branching index (LCBI) | EQUISTAR CHEMICALS, LP | 2003-06-24 | — | — | US | disclosed |
| EP-1290044-A1 | ETHYLENE POLYMERIZATON PROCESS | Equistar Chemicals L.P. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-20020177675-A1 | Ethylene polymerization process | EQUISTAR CHEMICALS, LP | 2002-11-28 | — | — | US | disclosed |
| WO-2002094888-A1 | ETHYLENE POLYMERIZATION PROCESS | EQUISTAR CHEMICALS, LP (US) | 2002-11-28 | — | — | WO | disclosed |
| US-20020161144-A1 | Ethylene polymerization process | EQUISTAR CHEMICALS, LP | 2002-10-31 | — | — | US | disclosed |
| WO-2002079277-A1 | ETHYLENE POLYMERIZATION PROCESS | EQUISTAR CHEMICALS, LP (US) | 2002-10-10 | — | — | WO | disclosed |
| US-6403736-B1 | SUPPORTING GROUP 3-10 METAL CATALYST CONTAINING BORAARYL LIGAND ONTO INORGANIC OXIDE OR CHLORIDE OR POLYMER, PREMIXING WITH TRIETHYLALUMINUM, POLYMERIZING OLEFIN IN PRESENCE OF CATALYST, ACTIVATOR AND TRIISOBUTYLALUMINUM SCAVENGER | EQUISTAR CHEMICALS, LP | 2002-06-11 | — | — | US | disclosed |
| WO-2001096420-A1 | ETHYLENE POLYMERIZATON PROCESS | EQUISTAR CHEMICALS, L.P. (US) | 2001-12-20 | — | — | WO | disclosed |