Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625535 | 0.91 | SMN1; SMN2 (0.64) | SMN1; SMN2PDCD1CD274ALDH1A1TSHR | |
| SCHEMBL11592004 | 0.88 | MEN1 (0.56) | SMN1; SMN2CA2CA1ALDH1A1DRD4 | |
| SCHEMBL6277988 | 0.83 | CA2 (0.61) | CA2CA1ALDH1A1DRD4SCN8A | |
| SCHEMBL11594250 | 0.82 | MAOA (0.61) | SCN8ASIGMAR1 | |
| SCHEMBL29017807 | 0.80 | CA2 (0.60) | CA2CA1ALDH1A1BCHEKMT2A | |
| SCHEMBL8252697 | 0.80 | L3MBTL1 (0.56) | SMN1; SMN2PDCD1CD274ALDH1A1TSHR | |
| SCHEMBL3622998 | 0.80 | HRH4 (0.52) | SMN1; SMN2CA2CA1ALDH1A1DRD4 | |
| SCHEMBL6081998 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2PDCD1CD274ALDH1A1TSHR | |
| SCHEMBL2263025 | 0.80 | CHRM2 (0.64) | SMN1; SMN2PDCD1CD274CA2CA1 | |
| SCHEMBL5853981 | 0.80 | CYP1A2 (0.56) | SMN1; SMN2PDCD1CD274CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3758737-A1 | IL-6 ANTIBODIES AND FUSION CONSTRUCTS AND CONJUGATES THEREOF | Kodiak Sciences Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| CN-102585844-B | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element containing same | CHI MEI CORP | 2014-03-12 | — | — | CN | disclosed |
| US-8455692-B2 | Process for resolution of 1-(3-hydroxyphenyl)-2-methylamino ethanol | Divi's Laboratories, Ltd. (IN) | 2013-06-04 | — | — | US | disclosed |
| CN-102585844-A | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element containing same | CHI MEI CORP | 2012-07-18 | — | — | CN | disclosed |
| US-20120108848-A1 | PROCESS FOR RESOLUTION OF 1-(3-HYDROXYPHENYL)-2-METHYLAMINO ETHANOL | DIVI'S LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| EP-2315615-A2 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR USING PERSULFATES, PERBORATES OR PERCARBONATES | L'Oréal (FR) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010023560-A2 | METHODS AND KITS FOR PROVIDING LIFT AND THEN A PERMANENT COLOR TO HAIR | L'OREAL (FR) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010011599-A2 | PIMETHIXENE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOGENEX INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2009148874-A2 | GAMMA-LACTAM COMPOUNDS FOR PROMOTING BONE GROWTH | OSTEOGENEX INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| US-7589127-B2 | Aminoalkylphenols, methods of using and making the same | MERCK & CO., INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20040122782-A1 | Process for determining the composition of a dye product | L'OREAL (FR) | 2004-06-24 | — | — | US | disclosed |
| CN-1426777-A | Composition for oxidation dyeing of keratin fibre and method for dyeing keratin fibre | OREAL (FR) | 2003-07-02 | — | — | CN | disclosed |
| US-6004669-A | ELECTROSTATIC CHARGING MEMBER, UNIFORMLY DISPERSED IN A MODIFIED RESIN AS A BASE POLYMER BEING MODIFIED BY AN AMINE GROUP WHICH HAS AN ACID-BASE INTERACTION WITH THE OXIDATION-PROCESSED ELECTRICALLY-CONDUCTING AGENT, | FUJI XEROX CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| US-5852071-A | Biphenyl additive for improvement in urethane foundry binders | BORDEN CHEMICAL, INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0863927-A1 | RAPID-FOAMING FOAM FOR PREFABRICATED SYSTEM BUILDING | RATHOR AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| US-5792802-A | IMPROVEMENTS IN HUMIDITY RESISTANCE, MOLD RELEASE AND HOT STRENGTH | BORDEN CHEMICAL, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| US-5744518-A | Biphenyl additive for improvement in urethane foundry binders | BORDEN CHEMICAL, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1997020876-A1 | RAPID-FOAMING FOAM FOR PREFABRICATED SYSTEM BUILDING | RATHOR AG (CH) | 1997-06-12 | — | — | WO | disclosed |
| EP-0695594-A2 | Biphenyl additive for improvement in urethane foundry binders | Borden, Inc. (US) | 1996-02-07 | — | — | EP | disclosed |
| CN-87101828-A | BROMINE-CONTAINING POLYOLS | — | 1987-11-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108848-A1 | PROCESS FOR RESOLUTION OF 1-(3-HYDROXYPHENYL)-2-METHYLAMINO ETHANOL | ADH1A, CYP2E1, ADH1C | SMN1; SMN2 2620/4885PDCD1 4727/4885CD274 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.