Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | MPL | P40238 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.52 |
| ▸ | KDM4B | O94953 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18094534 | 0.82 | LMNA (0.55) | ADORA3LMNAMEN1MAPTKMT2A | |
| SCHEMBL18230323 | 0.81 | ADORA3 (0.79) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL18230481 | 0.81 | STAT3 (0.47) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL18230436 | 0.80 | GRM1 (0.61) | GRM1MPLADORA3KDM4AKDM4B | |
| SCHEMBL31265595 | 0.77 | PARP1 (0.74) | MPLADORA3LMNAGSTO1MEN1 | |
| SCHEMBL31134882 | 0.74 | USP2 (0.54) | MPLALDH1A1LMNAGSTO1MEN1 | |
| SCHEMBL18113883 | 0.73 | ADORA3 (0.46) | GRM1MPLADORA3KDM4AKDM4B | |
| SCHEMBL4746841 | 0.73 | ALDH1A1 (0.63) | ADORA3ALDH1A1LMNAMEN1MAPT | |
| SCHEMBL14102514 | 0.72 | KMT2A (0.67) | GRM1MPLALDH1A1LMNAMEN1 | |
| SCHEMBL21484872 | 0.72 | ABL1 (0.53) | GRM1MPLADORA3KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |