Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NCS1 | P62166 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230364 | 0.83 | ADORA2A (0.42) | RAB9ANPC1PKMPAX8L3MBTL1 | |
| SCHEMBL18230488 | 0.81 | ADORA2A (0.46) | RAB9ANPC1L3MBTL1TRPV4MEN1 | |
| SCHEMBL18230494 | 0.81 | NPC1 (0.49) | RAB9ANPC1PKMPAX8L3MBTL1 | |
| SCHEMBL18230411 | 0.80 | ADORA3 (0.61) | RAB9ANPC1TRPV4MEN1KMT2A | |
| SCHEMBL18230342 | 0.80 | ADORA2A (0.44) | L3MBTL1TRPV4GAAMEN1KMT2A | |
| SCHEMBL18230254 | 0.79 | TRPV4 (0.52) | RAB9ANPC1TRPV4MEN1KMT2A | |
| SCHEMBL18230353 | 0.78 | PTGES (0.49) | RAB9ANPC1PKML3MBTL1TRPV4 | |
| SCHEMBL18094560 | 0.78 | MAPT (0.59) | RAB9ANPC1PKMPAX8L3MBTL1 | |
| SCHEMBL18230512 | 0.77 | GRM1 (0.53) | RAB9ANPC1TRPV4MEN1KMT2A | |
| SCHEMBL18230397 | 0.76 | KDM4E (0.50) | RAB9ANPC1PKML3MBTL1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |