Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230321 | 0.94 | ADORA2A (0.48) | ADORA2AADORA1TRPV4GRM1TRPV1 | |
| SCHEMBL18230361 | 0.91 | ADORA3 (0.46) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230513 | 0.90 | TLR7 (0.49) | ADORA2AADORA1TRPV1MAPTLMNA | |
| SCHEMBL18230296 | 0.88 | TRPV1 (0.54) | ADORA2AADORA1TRPV4GRM1TRPV1 | |
| SCHEMBL18230282 | 0.88 | TRPV4 (0.56) | ADORA2AADORA1TRPV4ADORA3KAT6A | |
| SCHEMBL18230233 | 0.85 | ADORA2A (0.48) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230284 | 0.83 | ADORA2A (0.39) | ADORA2AADORA1TRPV4ADORA3MAPT | |
| SCHEMBL18230404 | 0.82 | ADORA2A (0.47) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230353 | 0.81 | PTGES (0.49) | ADORA2AADORA1TRPV4GRM1ADORA3 | |
| SCHEMBL18230414 | 0.81 | ADORA2A (0.51) | ADORA2AADORA1TRPV4ADORA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |