SCHEMBL18235835

SCHEMBL18235835

CC(=O)O/N=C(/C)C(=O)c1ccc2c(c1)C(C)(C)c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 13/20 0.41
▸ HTR7 P34969 4/20 0.37
▸ HTR2B P41595 4/20 0.37
▸ POLB P06746 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20032517 1.00 PDK2 (0.41) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL18012799 0.93 MAPT (0.40) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL20032405 0.91 PDK2 (0.40) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL18235842 0.88 PDK2 (0.38) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL22782112 0.86 PDK2 (0.40) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL18012798 0.85 KMT2A (0.47) MAPTSMN1; SMN2KMT2AL3MBTL1
SCHEMBL18235838 0.84 PDK2 (0.38) PDK2HTR7HTR2BKMT2AL3MBTL1
SCHEMBL18222911 0.84 PDK2 (0.39) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL20032518 0.84 PDK2 (0.39) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL18235843 0.84 PDK2 (0.39) PDK2HTR7HTR2BPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9873663-B2 Fluorenyl β-oxime ester compounds, photopolymerization initiator and photoresist composition containing the same SAMYANG CORPORATION (KR) 2018-01-23 — — US disclosed
US-9873663-B2 Fluorenyl β-oxime ester compounds, photopolymerization initiator and photoresist composition containing the same SAMYANG CORPORATION (KR) 2018-01-23 — — US disclosed
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME SAMYANG CORPORATION (KR) 2016-11-17 — — US disclosed
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME SAMYANG CORPORATION (KR) 2016-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PFAS PDK2 981/4885HTR7 3122/4885HTR2B 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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