SCHEMBL9921061

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12611740	0.94	HTR1A (0.42)	MAPK14GRM5HTR1AHTR7KDM4E
	SCHEMBL12611737	0.93	GRM5 (0.40)	MAPK14GRM5HTR1AHTR7KDM4E
	SCHEMBL20276077	0.90	MAPK14 (0.38)	MAPK14GRM5HTR1AHTR7KDM4E
	SCHEMBL20276062	0.90	L3MBTL1 (0.41)	MAPK14GRM5KDM4EATML3MBTL1
	SCHEMBL20276095	0.89	MAPK14 (0.38)	MAPK14GRM5HTR1AHTR7KDM4E
	SCHEMBL20276075	0.89	L3MBTL1 (0.40)	MAPK14GRM5KDM4EATML3MBTL1
	SCHEMBL12611875	0.88	KDM4E (0.37)	GRM5KDM4EATML3MBTL1DHFR
	SCHEMBL9920673	0.87	MAPK14 (0.41)	MAPK14KDM4EATML3MBTL1DHFR
	SCHEMBL12613636	0.86	MCL1 (0.37)	MAPK14GRM5HTR1AHTR7KDM4E
	SCHEMBL12611732	0.86	GLO1 (0.34)	KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.