Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL1824629

N#Cc1ccc(S(=O)[O-])cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
MAOB P27338 4/20 0.42
MAOA P21397 3/20 0.42
OPRD1 P41143 2/20 0.36
MAPT P10636 2/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LSS P48449 1/20 0.33
EEF2K O00418 1/20 0.33
CYP19A1 P11511 2/20 0.33
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1584344 0.82 CA2 (0.47) TSHRMAOBMAOACA1CA2
Potassium Ion SCHEMBL11326413 0.82 CA2 (0.43) TSHRCA1CA2ALDH1A1CYP19A1
SCHEMBL5407516 0.80 TSHR (0.42) TSHRMAOBMAOAOPRD1MAPT
SCHEMBL29404656 0.80 TSHR (0.59) TSHRMAOBMAOAOPRD1MAPT
Bromide SCHEMBL7883475 0.78 TSHR (0.56) TSHRMAOBMAOAOPRD1MAPT
Hydrochloric Acid SCHEMBL7247582 0.78 TSHR (0.56) TSHRMAOBMAOAOPRD1MAPT
SCHEMBL11325583 0.72 TSHR (0.41) TSHRMAOBMAOAMAPTCA1
SCHEMBL11325604 0.72 TSHR (0.41) TSHRMAOBMAOAMAPTCA1
Tetraphenylphosphonium SCHEMBL7178151 0.71 EPHX2 (0.39) TSHRALDH1A1
Tetraphenylphosphonium SCHEMBL7178157 0.69 EPHX2 (0.37) TSHRCA2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1668039-B1 ARYLSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS 3M INNOVATIVE PROPERTIES CO (US) 2012-12-05 EP claimed
US-7732633-B2 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-06-08 US claimed
US-20090203904-A1 ARYLSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS 3M INNOVATIVE PROPERTIES COMPANY 2009-08-13 US claimed
US-20070249749-A1 ARYSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS KALGUTKAR RAJDEEP S 2007-10-25 US claimed
US-20050070624-A1 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY 2005-03-31 US claimed
EP-1668039-B1 ARYLSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS 3M INNOVATIVE PROPERTIES CO (US) 2012-12-05 EP disclosed
EP-1668038-B1 ARYLSULFINATE SALTS IN INITIATOR SYSTEMS FOR POLYMERIC REACTIONS 3M INNOVATIVE PROPERTIES CO (US) 2011-05-04 EP disclosed
US-7732633-B2 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-06-08 US disclosed
US-20090203904-A1 ARYLSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS 3M INNOVATIVE PROPERTIES COMPANY 2009-08-13 US disclosed
US-7541389-B2 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-02 US disclosed
US-7329692-B2 Arylsulfinate salts in initiator systems for polymeric reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-02-12 US disclosed
US-20070249749-A1 ARYSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS KALGUTKAR RAJDEEP S 2007-10-25 US disclosed
US-7064152-B2 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-20 US disclosed
EP-1668038-A1 ARYLSULFINATE SALTS IN INITIATOR SYSTEMS FOR POLYMERIC REACTIONS 3M Innovative Properties Company (US) 2006-06-14 EP disclosed
US-20060111462-A1 ARYLSULFINATE SALTS IN INITIATOR SYSTEMS FOR POLYMERIC REACTIONS 3M INNOVATIVE PROPERTIES COMPANY 2006-05-25 US disclosed
US-7030169-B2 Arylsulfinate salts in initiator systems for polymeric reactions 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-18 US disclosed
WO-2005035590-A1 ARYLSULFINATE SALTS IN INITIATOR SYSTEMS FOR POLYMERIC REACTIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-04-21 WO disclosed
US-20050070624-A1 Arylsulfinate salts in photoinitiator systems for polymerization reactions 3M INNOVATIVE PROPERTIES COMPANY 2005-03-31 US disclosed
US-20050070622-A1 Arylsulfinate salts in initiator systems for polymeric reactions 3M INNOVATIVE PROPERTIES COMPANY 2005-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203904-A1 ARYLSULFINATE SALTS IN PHOTOINITIATOR SYSTEMS FOR POLYMERIZATION REACTIONS TST, ARSA, MPST TSHR 4639/4885MAOB 1576/4885MAOA 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.