SCHEMBL18248017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19088483	1.00	LTA4H (0.39)	LTA4HLAP3ALDH1A1MAPK1L3MBTL1
	SCHEMBL21160112	0.89	MMP12 (0.39)	LTA4HLAP3ALDH1A1MAPK1L3MBTL1
	SCHEMBL23279458	0.87	LTA4H (0.39)	LTA4HLAP3ALDH1A1MAPK1L3MBTL1
	SCHEMBL18256440	0.87	LTA4H (0.39)	LTA4HLAP3ALDH1A1MAPK1L3MBTL1
	SCHEMBL24093727	0.86	PPARG (0.39)	LTA4HLAP3ALDH1A1PPARGPPARA
	SCHEMBL20586636	0.83	KDM6B (0.40)	PPARGPPARA
	SCHEMBL18248189	0.83	KDM6B (0.40)	PPARGPPARA
	SCHEMBL22502766	0.82	FFAR1 (0.39)	—
	SCHEMBL19066759	0.80	HCAR2 (0.39)	ALDH1A1MAPK1L3MBTL1DDB1CRBN
	SCHEMBL23279538	0.77	LTA4H (0.40)	LTA4HLAP3ALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.