Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249422 | 0.85 | ELANE (0.48) | ELANETSHRPRTN3LMNAMAPT | |
| SCHEMBL20164248 | 0.85 | PTGS2 (0.42) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18249478 | 0.83 | TSHR (0.41) | ELANETSHRPRTN3LMNANPSR1 | |
| SCHEMBL20164269 | 0.82 | TSHR (0.44) | ELANETSHRLMNAMAPTALDH1A1 | |
| SCHEMBL18249465 | 0.81 | KMT2A (0.45) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL20164266 | 0.77 | SMN1; SMN2 (0.41) | TSHRLMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL20164247 | 0.77 | KMT2A (0.45) | ELANELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL20164208 | 0.74 | LMNA (0.47) | ELANELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL18249383 | 0.74 | TSHR (0.38) | ELANETSHRPRTN3LMNAMAPT | |
| SCHEMBL997654 | 0.73 | SIGMAR1 (0.43) | TSHRLMNANPSR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |