Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809714 | 0.85 | KCNH2 (0.41) | PPARGPPARDPPARACNR2PTGES | |
| SCHEMBL11943723 | 0.85 | SLC6A2 (0.45) | FDFT1 | |
| SCHEMBL18909839 | 0.82 | PPARG (0.45) | PPARGPPARDPPARAMTNR1AMTNR1B | |
| SCHEMBL12634447 | 0.81 | KCNH2 (0.44) | PPARGPPARDPPARAMTNR1AMTNR1B | |
| SCHEMBL20006868 | 0.80 | PTGER1 (0.44) | MTNR1AMTNR1BL3MBTL1HTR1A | |
| SCHEMBL73987 | 0.79 | MTNR1A (0.45) | PPARGPPARDPPARAMTNR1AMTNR1B | |
| SCHEMBL18255266 | 0.79 | FAAH (0.46) | PPARGPPARDPPARAFAAHHTT | |
| SCHEMBL11919293 | 0.76 | L3MBTL1 (0.45) | PPARGPPARDPPARAKCNH2FAAH | |
| SCHEMBL18255231 | 0.75 | PPARG (0.40) | PPARGPPARDPPARACNR2MTNR1A | |
| SCHEMBL18255264 | 0.75 | PPARG (0.40) | PPARGPPARDPPARACNR2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183809-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | 浙江奥翔药业股份有限公司 | 2016-11-24 | — | — | WO | disclosed |