Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316795 | 0.87 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL16797742 | 0.85 | LMNA (0.45) | PTGER1HTR1ADRD2LMNAL3MBTL1 | |
| SCHEMBL20179453 | 0.82 | MGLL (0.52) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL18697557 | 0.82 | ACLY (0.43) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL18894534 | 0.82 | HTR1A (0.53) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL11943723 | 0.80 | SLC6A2 (0.45) | LMNA | |
| SCHEMBL18255262 | 0.80 | PPARG (0.42) | HTR1AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL6216285 | 0.79 | ELANE (0.53) | HTR1ADRD2LMNAL3MBTL1FFAR1 | |
| SCHEMBL24316909 | 0.78 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL16797594 | 0.76 | HTR1A (0.53) | HTR1ADRD2LMNAL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |
| EP-3299364-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2018-03-28 | — | — | EP | disclosed |