Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255231 | 1.00 | PPARG (0.40) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL18909839 | 0.83 | PPARG (0.45) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL18255266 | 0.80 | FAAH (0.46) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL12634447 | 0.79 | KCNH2 (0.44) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL19988043 | 0.78 | HTR1A (0.46) | LMNA | |
| SCHEMBL19988047 | 0.78 | HTR1A (0.46) | LMNA | |
| SCHEMBL73987 | 0.77 | MTNR1A (0.45) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL11919293 | 0.77 | L3MBTL1 (0.45) | PPARGPPARDPPARAFAAHLTB4R | |
| SCHEMBL18255255 | 0.76 | LTB4R (0.42) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL3808282 | 0.76 | LTB4R (0.57) | PPARGPPARDPPARALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183809-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | 浙江奥翔药业股份有限公司 | 2016-11-24 | — | — | WO | disclosed |