Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255466 | 1.00 | CYP1A2 (0.37) | CYP1A2GRM2NAAATDP1GBA1 | |
| SCHEMBL13761276 | 0.85 | FAAH (0.49) | — | |
| SCHEMBL14389283 | 0.85 | FAAH (0.49) | — | |
| SCHEMBL16903986 | 0.83 | CYP1A2 (0.40) | CYP1A2GRM2 | |
| SCHEMBL134600 | 0.77 | ALDH1A1 (0.43) | GRM2 | |
| SCHEMBL131142 | 0.77 | ALDH1A1 (0.43) | GRM2 | |
| SCHEMBL14714256 | 0.77 | PABPC1 (0.38) | NAAATDP1GBA1 | |
| SCHEMBL11960166 | 0.75 | TDP1 (0.35) | TDP1GBA1 | |
| SCHEMBL10651147 | 0.74 | GBA1 (0.34) | NAAAGBA1 | |
| SCHEMBL4317709 | 0.72 | ALDH1A1 (0.44) | CYP1A2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340328-A1 | HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340328-A1 | HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE | BMP1, BMPR1A, BMPR2 | CYP1A2 1422/4885GRM2 3478/4885NAAA 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.