SCHEMBL18256246

SCHEMBL18256246

CCCCN(C(=O)OCC)C(C)CC(C)OC(=O)CC(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
FAAH O00519 4/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20164268 0.79 MMP1 (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL20168886 0.79 ALDH1A1 (0.37) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL18249450 0.77 LMNA (0.44) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL18256242 0.77 TSHR (0.43) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL21159624 0.77 ALDH1A1 (0.40) MMP1MMP2MMP3ALDH1A1LMNA
SCHEMBL28482683 0.76 ALDH1A1 (0.40) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL21522901 0.75 DNM1 (0.36) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL18256248 0.75 TSHR (0.41) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL18256243 0.75 TSHR (0.41) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL18249376 0.75 ALDH1A1 (0.36) MMP1MMP2MMP3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298048-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-07-03 EP disclosed
EP-3298048-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-07-03 EP disclosed
US-10221256-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-03-05 US disclosed
US-10221256-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-03-05 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed
WO-2016184884-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-11-24 WO disclosed