SCHEMBL20164268

SCHEMBL20164268

CCOC(=O)N(C)C(C)CC(C)OC(=O)CC(C)C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
CYP19A1 P11511 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17326989 0.83 ALDH1A1 (0.39)
SCHEMBL20164264 0.83 TSHR (0.38)
SCHEMBL18256246 0.79 MMP1 (0.33) MMP1MMP2MMP3MMP9MMP13
SCHEMBL29768259 0.78 CHRNB2 (0.44)
SCHEMBL19107414 0.76 MGAM (0.36)
SCHEMBL20031936 0.75 CHRNB2 (0.39) MEN1KMT2A
SCHEMBL20180238 0.75 MGAM (0.41)
SCHEMBL18249490 0.74 CHRNB2 (0.36) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18249468 0.73 LMNA (0.42) MEN1KMT2A
SCHEMBL21522876 0.73 TSHR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298048-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-07-03 EP disclosed
US-10221256-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-03-05 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed