Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717106 | 0.76 | PTGS2 (0.35) | ACACBCNR2HCRTR1HCRTR2SCN9A | |
| SCHEMBL2714834 | 0.73 | ALDH1A1 (0.34) | ACACBCNR2HCRTR1HCRTR2SCN9A | |
| SCHEMBL28840392 | 0.73 | CNR2 (0.34) | ACACBCNR2MEN1MAPTKMT2A | |
| SCHEMBL2716649 | 0.72 | GAA (0.46) | CNR2SCN9ALMNASMN1; SMN2 | |
| SCHEMBL27914078 | 0.72 | MMP13 (0.42) | ACACBCNR2RIPK1MEN1KMT2A | |
| SCHEMBL2716490 | 0.71 | L3MBTL1 (0.38) | CNR2HCRTR1HCRTR2SCN9AMEN1 | |
| SCHEMBL2715621 | 0.70 | SCN9A (0.43) | RIPK1SCN9A | |
| SCHEMBL27913875 | 0.70 | KCNH2 (0.47) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL2714362 | 0.70 | GRK2 (0.44) | RIPK1SCN9AMAPT | |
| SCHEMBL27931827 | 0.69 | CNR2 (0.34) | ACACBCNR2RIPK1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630122-B1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2016-11-30 | — | — | EP | disclosed |