Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931782 | 0.84 | KCNH2 (0.35) | CNR2MAPTDGAT1 | |
| SCHEMBL27931827 | 0.83 | CNR2 (0.34) | CNR2ACACB | |
| Pyrazinamide SCHEMBL28093474 | 0.82 | ADORA3 (0.40) | CNR2KMT2ACYP1A2KDM4EDGAT1 | |
| SCHEMBL2714834 | 0.81 | ALDH1A1 (0.34) | CNR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2717106 | 0.81 | PTGS2 (0.35) | CNR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL28130155 | 0.75 | MEN1 (0.36) | CNR2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL27913875 | 0.75 | KCNH2 (0.47) | KMT2AMAPTGAA | |
| SCHEMBL27914078 | 0.75 | MMP13 (0.42) | CNR2MEN1KMT2AACACB | |
| SCHEMBL27931958 | 0.74 | CYP1A2 (0.36) | CNR2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL18258951 | 0.73 | ACACB (0.36) | CNR2MEN1KMT2AMAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |