Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | POLD1 | P28340 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | TK1 | P04183 | 4/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279551 | 0.88 | TK1 (0.44) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL8692891 | 0.85 | POLB (0.51) | POLBPOLA1POLD1P2RY6TK1 | |
| Phosphoric Acid SCHEMBL9086402 | 0.81 | TK1 (0.39) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL3813740 | 0.80 | LMNA (0.41) | TK1LMNATSHRALBPKM | |
| SCHEMBL6689098 | 0.78 | TK1 (0.53) | POLBPOLA1POLD1P2RY6P2RY14 | |
| SCHEMBL28496626 | 0.74 | ABCG2 (0.47) | ABCG2 | |
| SCHEMBL18258987 | 0.74 | LMNA (0.32) | TK1LMNATSHRALBPKM | |
| SCHEMBL10481879 | 0.70 | LMNA (0.37) | TK1LMNATSHRALBPKM | |
| SCHEMBL10481880 | 0.70 | LMNA (0.37) | TK1LMNATSHRALBPKM | |
| SCHEMBL6757641 | 0.70 | LMNA (0.36) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485395-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | Biota, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003072757-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA, INC. (US) | 2003-09-04 | — | — | WO | disclosed |