Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263186 | 1.00 | ALOX5 (0.46) | ALOX5ALDH1A1TRPM8MTORHPGD | |
| SCHEMBL17962437 | 0.91 | KMT2A (0.40) | ALOX5ALDH1A1TRPM8MTORHPGD | |
| SCHEMBL18263192 | 0.76 | TRPM8 (0.38) | ALOX5ALDH1A1TRPM8MTORMEN1 | |
| SCHEMBL18263194 | 0.76 | TRPM8 (0.38) | ALOX5ALDH1A1TRPM8MTORMEN1 | |
| SCHEMBL28338187 | 0.74 | TRPM8 (0.39) | ALOX5TRPM8MTORMEN1KMT2A | |
| SCHEMBL28361461 | 0.71 | LMNA (0.37) | ALOX5TRPM8KMT2ALMNA | |
| SCHEMBL28171272 | 0.71 | LMNA (0.37) | ALOX5TRPM8KMT2ALMNA | |
| SCHEMBL28364875 | 0.71 | LMNA (0.37) | ALOX5TRPM8KMT2ALMNA | |
| SCHEMBL4465930 | 0.71 | ALOX5 (0.57) | ALOX5ALDH1A1TRPM8MTORHPGD | |
| SCHEMBL29009661 | 0.71 | ALOX5 (0.45) | ALOX5ALDH1A1TRPM8MTORHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108416-B | Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-107108416-A | A kind of preparation method of 1,2 Bicyclopropyl ethyl -phenol and its optical isomer | 四川海思科制药有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016188490-A1 | METHOD FOR PREPARING 1,2-DICYCLOPROPYLETHYLPHENOL AND OPTICAL ISOMER THEREOF | 四川海思科制药有限公司 | 2016-12-01 | — | — | WO | disclosed |