Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263194 | 1.00 | TRPM8 (0.38) | TRPM8ALOX5NOTUMRECQLPOLB | |
| SCHEMBL28392659 | 0.91 | ALOX15 (0.37) | TRPM8ALOX5NOTUMRECQLPOLB | |
| SCHEMBL28171398 | 0.88 | FFAR1 (0.33) | TRPM8ALOX5NOTUMRECQLPOLB | |
| SCHEMBL28171399 | 0.88 | FFAR1 (0.33) | TRPM8ALOX5NOTUMRECQLPOLB | |
| SCHEMBL18263185 | 0.76 | ALOX5 (0.46) | TRPM8ALOX5RECQLALDH1A1KMT2A | |
| SCHEMBL18263186 | 0.76 | ALOX5 (0.46) | TRPM8ALOX5RECQLALDH1A1KMT2A | |
| SCHEMBL28338187 | 0.74 | TRPM8 (0.39) | TRPM8ALOX5NOTUMRECQLKMT2A | |
| SCHEMBL28361461 | 0.71 | LMNA (0.37) | TRPM8ALOX5NOTUMKMT2ALMNA | |
| SCHEMBL28364875 | 0.71 | LMNA (0.37) | TRPM8ALOX5NOTUMKMT2ALMNA | |
| SCHEMBL28167397 | 0.71 | LMNA (0.37) | TRPM8ALOX5NOTUMKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108416-B | Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-107108416-A | A kind of preparation method of 1,2 Bicyclopropyl ethyl -phenol and its optical isomer | 四川海思科制药有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016188490-A1 | METHOD FOR PREPARING 1,2-DICYCLOPROPYLETHYLPHENOL AND OPTICAL ISOMER THEREOF | 四川海思科制药有限公司 | 2016-12-01 | — | — | WO | disclosed |