Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | SI | P14410 | 3/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21251472 | 0.92 | MAPT (0.68) | MAPTALOX5PTGS1GAAMGAM | |
| SCHEMBL18265483 | 0.83 | MTNR1A (0.70) | MAPTALOX5PTGS1TRPA1MTNR1A | |
| SCHEMBL21251473 | 0.82 | MAPT (0.62) | MAPTALOX5PTGS1TRPA1MTNR1A | |
| SCHEMBL30887916 | 0.82 | CYP1A1 (0.58) | MAPTPTGS1GAAHTTTUBB1 | |
| SCHEMBL2004805 | 0.82 | CYP1A1 (0.58) | MAPTPTGS1GAAHTTTUBB1 | |
| SCHEMBL4299632 | 0.82 | CYP1A1 (0.58) | MAPTPTGS1GAAHTTTUBB1 | |
| SCHEMBL18265491 | 0.81 | TRPA1 (0.71) | MAPTALOX5PTGS1GAAMGAM | |
| SCHEMBL18265474 | 0.78 | MAPT (0.51) | MAPTALOX5PTGS1GAAMGAM | |
| SCHEMBL18010182 | 0.78 | ALOX5 (0.57) | MAPTALOX5GAATRPA1MTNR1A | |
| SCHEMBL16692680 | 0.78 | ALOX5 (0.57) | MAPTALOX5GAATRPA1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |
| EP-3097904-A1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | Affichem (FR) | 2016-11-30 | — | — | EP | disclosed |