Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163740 | 1.00 | LMNA (0.40) | LMNAGAANPC1RAB9ATRPV1 | |
| SCHEMBL6430159 | 0.81 | LMNA (0.38) | LMNAGAANPC1RAB9ATRPV1 | |
| SCHEMBL6430156 | 0.77 | LMNA (0.41) | LMNAGAANPC1RAB9APDE2A | |
| SCHEMBL1223403 | 0.77 | CYP11B1 (0.31) | — | |
| SCHEMBL1223400 | 0.77 | CYP11B1 (0.31) | — | |
| SCHEMBL1827197 | 0.73 | HCRTR1 (0.33) | — | |
| SCHEMBL1822223 | 0.73 | LMNA (0.35) | LMNA | |
| SCHEMBL1822534 | 0.73 | LMNA (0.35) | LMNA | |
| SCHEMBL1822226 | 0.73 | LMNA (0.35) | LMNA | |
| SCHEMBL1824268 | 0.73 | HCRTR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758896-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | Bayer CropScience GmbH (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123726-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-12-29 | — | — | WO | disclosed |
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | PRDX1, CYP4X1, PRDX4 | LMNA 2335/4885GAA 2629/4885NPC1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.