Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766167 | 0.80 | ALDH1A1 (0.42) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL362051 | 0.80 | ALDH1A1 (0.42) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL38652412 | 0.78 | DGAT1 (0.36) | ALDH1A1KDM1AKDM1BCYP2A6TDP1 | |
| SCHEMBL30770922 | 0.76 | PHOSPHO1 (0.32) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL379916 | 0.76 | ACHE (0.35) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL3610893 | 0.76 | NFE2L2 (0.36) | ALDH1A1NFE2L2CYP1A2CYP2A6TDP1 | |
| SCHEMBL1429441 | 0.75 | CA3 (0.42) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL27873065 | 0.74 | CA3 (0.46) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL636066 | 0.72 | NFE2L2 (0.42) | CA9CA14NFE2L2CYP1A2KDM4E | |
| SCHEMBL165158 | 0.71 | ACHE (0.35) | CA3CA6CA5ACA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445879-B | Preparation method of Latricinib intermediate | 苏州立新制药有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-107556226-B | Preparation method of Latricinib intermediate | 苏州明锐医药科技有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-109354578-A | It is a kind of for Buddhist nun's intermediate and for the synthetic method of Buddhist nun | 浙江师范大学 | 2019-02-19 | — | — | CN | claimed |
| CN-105367556-A | Synthetic method of antifungal drug intermediate (2R,3S) -1- (1,2, 4-triazolyl) -2-difluorophenyl-2, 3-epoxybutane | NANTONG NUOTAI BIOLOGICAL PHARMACEUTICAL CO LTD | 2016-03-02 | — | — | CN | claimed |
| US-11059827-B2 | Compounds and compositions useful for treating disorders related to NTRK | BLUEPRINT MEDICINES CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-11046697-B2 | Compounds and compositions useful for treating disorders related to NTRK | BLUEPRINT MEDICINES CORPORATION | 2021-06-29 | — | — | US | disclosed |
| CN-108137607-B | Compounds and compositions suitable for treating NTRK-related disorders | 缆图药品公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-112010901-A | (2, 5-difluorophenyl) diphenyl phosphine oxide and preparation method thereof | 上海应用技术大学 | 2020-12-01 | — | — | CN | disclosed |
| CN-107445879-B | Preparation method of Latricinib intermediate | 苏州立新制药有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-107556226-B | Preparation method of Latricinib intermediate | 苏州明锐医药科技有限公司 | 2020-06-30 | — | — | CN | disclosed |
| US-10370379-B2 | Compounds and compositions useful for treating disorders related to NTRK | BLUEPRINT MEDICINES CORPORATION (US) | 2019-08-06 | — | — | US | disclosed |
| US-20190169194-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO NTRK | BLUEPRINT MEDICINES CORPORATION | 2019-06-06 | — | — | US | disclosed |
| CN-1313288-A | Preparation of 4(fluorated aromatic radical) boron derivatives | NIPPON CATALYTIC CHEM IND (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1313289-A | Preparation of 4(fluorated aromatic radical) boron derivatives | NIPPON CATALYTIC CHEM IND (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1295074-A | Prep. of boron tetra [fluoro aryl] compound | NIPPON CATALYTIC CHEM IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1295073-A | Prep. of boron [fluoroaryl] compound | NIPPON CATALYTIC CHEM IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| US-6057480-A | Process for preparing fluoroaryl magnesium derivative and process for preparing (fluoroaryl) borane compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| CN-1180705-A | Method for producing [ fluoroaryl ] boron compound and method for producing tetrakis [ fluoroaryl ] boron derivative | NIPPON CATALYTIC CHEM IND (JP) | 1998-05-06 | — | — | CN | disclosed |
| EP-0838466-A2 | Producing process of (fluoroaryl) borane compound and producing process of tetrakis (fluoroaryl) borate derivative | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0825195-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED ARYLMAGNESIUM DERIVATIVES AND PROCESS FOR THE PREPARATION OF (FLUORINATED ARYL)BORON COMPOUNDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046697-B2 | Compounds and compositions useful for treating disorders related to NTRK | NTRK3, NTRK2, NTRK1 | CA3 4747/4885CA6 4699/4885CA5A 2648/4885 |
| US-11059827-B2 | Compounds and compositions useful for treating disorders related to NTRK | NTRK2, NTRK3, NTRK1 | CA3 4737/4885CA6 4807/4885CA5A 3297/4885 |
| US-10370379-B2 | Compounds and compositions useful for treating disorders related to NTRK | NTRK3, NTRK2, NTRK1 | CA3 4725/4885CA6 4699/4885CA5A 2444/4885 |
| US-20190169194-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO NTRK | NTRK3, NTRK2, NTRK1 | CA3 4747/4885CA6 4699/4885CA5A 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.